Autoruns : File not found unpicking keys, and drivers

I have some entries in my Autoruns that I would rather not be there, but when I try to uncheck them, I get the message "The system cannot find the file specified." What file is it looking for?

Also, I had several unwanted leftover parts of Asus Ai Suite II installed, but one of these is called AsIO.sys. As it is a driver I did not untick it per the warning in the top thread, however it does not seem to show up in devmgmt to remove. Is there another way to remove it?